On Alterations of Myocardial Lactic Dehydrogenase Isozyme by Coronary Ligation
نویسندگان
چکیده
منابع مشابه
Serum lactic acid dehydrogenase isozyme determination in myocardial infarction.
Introduction The principle of electrophoresis is known to be of great use in today's medicine and an expanding literature on this subject supports this view. Various methods for the electrophoretic separation of charged molecules have been developed in the past 15 years. Immunological and physicochemical studies have further increased knowledge of these electrophoretic fractions. On this princi...
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The clinical features presented by coronary occlusion with myocardial infarction are such that, together with electrocardiographic evidence, a correct diagnosis is usually possible (Price, 1950). Electrocardiographic changes, however, may sometimes be delayed, and in about 6 per cent of cases no change is detectable at all (Lancet, 1958). To assist in diagnosing these cases, enzyme tests have b...
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A method utilizing a general dehydrogenase reaction has been used to demonstrate early gross myocardial infarctions. The procedure takes advantage of substrate and enzyme loss from the damaged myocardium. In the viable muscle, where endogenous substrates, coenzymes, and dehydrogenases are present, reduction of Nitro-BT yields a dark blue formazan. Necrotic muscle fibres remain unstained by this...
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It has been shown that the size of myocardial infarction in rats created by coronary ligation technique is not uniform, varying from 4% to 65%. We hypothesized that infarct size variability induced by coronary artery ligation might be caused by coronary artery branching pattern. Coronary artery angiography was performed in 50 normal Lewis rats and in chronic myocardial infarction models in whic...
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In the subacute phase of myocardial infarction following coronary ligation in dogs, a relationship was noted between the extent of infarction and the degree of elevation of left ventricular end-diastolic pressure. Left ventricular filling pressure was consistently increased when 25% or more of the left ventricle was infarcted. Isoproterenol infusion resulted in enhanced left ventricular functio...
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ژورنال
عنوان ژورنال: Japanese Circulation Journal
سال: 1969
ISSN: 0047-1828,1347-4839
DOI: 10.1253/jcj.33.701